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Cimen Karasu Selected Research

dicarbine

5/2008Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.
9/2007Stobadine inhibits doxorubicin-induced apoptosis through a caspase-9 dependent pathway in P815 mastocytoma cells.
7/2007Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress.
3/2007Stobadine protects rat kidney against ischaemia/reperfusion injury.
1/2007Effects of antioxidant stobadine on protein carbonylation, advanced oxidation protein products and reductive capacity of liver in streptozotocin-diabetic rats: role of oxidative/nitrosative stress.
1/2005Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT.
1/2004Effect of stobadine on leukocyte free radical generation in streptozotocin-diabetic rats: comparison with vitamin E.

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Cimen Karasu Research Topics

Disease

10Hyperglycemia
01/2020 - 10/2002
8Diabetes Complications
05/2021 - 06/2002
3Diabetes Mellitus
04/2021 - 08/2002
2Neoplasms (Cancer)
06/2022 - 10/2013
2Parkinson Disease (Parkinson's Disease)
04/2021 - 01/2020
2Peripheral Nervous System Diseases (PNS Diseases)
01/2020 - 05/2019
2Body Weight (Weight, Body)
01/2020 - 01/2005
2Cataract (Cataracts)
10/2011 - 01/2005
2Diabetic Nephropathies (Diabetic Nephropathy)
01/2010 - 06/2003
2Diabetic Retinopathy (Retinopathy, Diabetic)
06/2008 - 07/2007
1Glioblastoma (Glioblastoma Multiforme)
06/2022
1Ischemia
09/2021
1Inflammation (Inflammations)
04/2021
1Blepharitis
08/2020
1Decompression Sickness (Bends)
08/2020
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
01/2020
1Insulinoma
11/2019
1Colonic Neoplasms (Colon Cancer)
11/2019
1Metrorrhagia (Spotting)
11/2019
1Diabetic Neuropathies (Diabetic Neuropathy)
05/2019
1Heart Diseases (Heart Disease)
10/2015
1Metabolic Diseases (Metabolic Disease)
10/2013
1Nervous System Diseases (Neurological Disorders)
03/2011
1Dyslipidemias (Dyslipidemia)
03/2011
1Premenstrual Syndrome (Premenstrual Tension)
02/2011
1Type 2 Diabetes Mellitus (MODY)
06/2008
1Weight Gain
12/2007
1Cardiovascular Abnormalities
12/2007
1Mastocytoma
09/2007
1Reperfusion Injury
03/2007
1Metabolic Syndrome (Dysmetabolic Syndrome X)
01/2004
1Obesity
01/2004
1Experimental Diabetes Mellitus
08/2002

Drug/Important Bio-Agent (IBA)

13AntioxidantsIBA
05/2021 - 06/2002
7dicarbineIBA
05/2008 - 01/2004
6Aldehyde Reductase (Aldose Reductase)IBA
05/2021 - 05/2008
6EnzymesIBA
05/2021 - 06/2002
6Glucose (Dextrose)FDA LinkGeneric
04/2021 - 01/2005
5Vitamin EFDA LinkGeneric
07/2007 - 10/2002
4polyolIBA
05/2021 - 10/2011
3cemtirestatIBA
01/2020 - 05/2019
3Proteins (Proteins, Gene)FDA Link
03/2011 - 01/2005
3Reactive Oxygen Species (Oxygen Radicals)IBA
01/2007 - 10/2002
2indoleIBA
05/2021 - 05/2019
2Streptozocin (Streptozotocin)FDA Link
01/2020 - 12/2007
2Triglycerides (Triacylglycerol)IBA
01/2020 - 12/2007
2Sorbitol (Yal)FDA Link
01/2020 - 05/2019
2CholesterolIBA
03/2011 - 12/2007
2Vitamin A (Retinol)FDA LinkGeneric
12/2007 - 06/2002
2LipidsIBA
12/2007 - 12/2002
2Insulin (Novolin)FDA Link
01/2004 - 06/2002
2CalciumIBA
06/2003 - 10/2002
1ThalliumIBA
06/2022
1Acetates (Acetic Acid Esters)FDA Link
06/2022
1salicylhydroxamic acid (SHAM)IBA
09/2021
1Oxidopamine (6 Hydroxydopamine)IBA
04/2021
1Blood Glucose (Blood Sugar)IBA
04/2021
1GelsIBA
08/2020
1Tea Tree OilIBA
08/2020
1Glutathione Transferase (Glutathione S-Transferase)IBA
08/2020
1LuteolinIBA
01/2020
1RotenoneIBA
01/2020
1Protoporphyrinogen Oxidase (Protox)IBA
11/2019
1Acetic Acid (Vinegar)FDA LinkGeneric
05/2019
1Thiobarbituric Acid Reactive SubstancesIBA
05/2019
1Xanthine OxidaseIBA
10/2015
1XanthineIBA
10/2015
1PolyphenolsIBA
10/2015
1Therapeutic UsesIBA
03/2012
1FlavonoidsIBA
10/2011
1CalpainIBA
10/2011
1Peptide Hydrolases (Proteases)FDA Link
10/2011
1QuercetinIBA
10/2011
1Oxygen (Dioxygen)IBA
03/2011
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
03/2011
1NitrogenIBA
03/2011
1FluvastatinFDA Link
03/2011
1Oxidants (Oxidizing Agents)IBA
02/2011
1Advanced Glycation End ProductsIBA
11/2010
1calpain 10IBA
06/2008
1Essential Fatty AcidsIBA
12/2007
1Docosahexaenoic AcidsIBA
12/2007
1Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA
12/2007
1Eicosapentaenoic AcidIBA
12/2007
1Cod Liver OilIBA
12/2007
1Doxorubicin (Adriamycin)FDA LinkGeneric
09/2007
1Caspase 9IBA
09/2007
1Retinaldehyde (Retinal)IBA
07/2007
1Free RadicalsIBA
01/2005
1Butylated Hydroxytoluene (BHT)IBA
01/2005
1Rosiglitazone (Avandia)FDA Link
01/2004
1ThiazolidinedionesIBA
01/2004
1Adenosine Triphosphatases (ATPase)IBA
06/2003
1CollagenIBA
08/2002
1Doxycycline (Periostat)FDA LinkGeneric
08/2002

Therapy/Procedure

3Therapeutics
06/2022 - 01/2010
1Glycemic Control
07/2007